megatomi.com for Dummies
megatomi.com for Dummies
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Our new Crystal clear+ tissue clearing system is the only technique that delipidates samples without having alter in morphology and with nominal effect on structural integrity.
Megatome is often a vibrating microtome meant to section a broad array of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With substantial blade vibrating frequency and minimized blade deflection, Megatome allows significant-throughput tissue sectioning with uniform area profile, and minimal tissue harm and information reduction.
Antibodies may possibly just take weeks to diffuse by means of just a few millimeters of tissue, using a steep labeling gradient from surface area to core.
Megatome is made for accuracy: the blade vibrates at a greater frequency and larger amplitude variety than other microtomes, and includes a distinctive deflection Manage mechanism.
SE employs a rotational electrical area to disperse extremely electromobile molecules (such as antibodies or surfactant micelles) throughout a porous sample without the need of harming electrically billed constructions inside the tissue. This enables two-four day clearing of intact organs,
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Megatome is often a novel microtome that permits for high-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with negligible tissue injury and information reduction.
It’s time for you to update your microtome to Megatome. With exact high-frequency slicing for an unmatched range of sample dimensions and types – from organoids and tumors to expanded tissues, sample arrays, and intact primate organs – Megatome is optimized megatomi.com for numerous apps.
The SmartSPIM light sheet microscope supplies unparalleled resolution and acquisition speed in the course of intact tissue volumes, whilst its modular style and design permits you to enhance and customize unique elements.
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Defend avoids the variability of hydrogel embedding and the data loss from PFA preservation, defending specimens for many rounds of processing.
Leverage the Distinct+ tissue clearing approach, in conjunction with eFLASH and patented stochastic electrotransport systems, to quickly very clear and label complete organs. Critical highlights and features consist of:
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